Cyclizine [is] used to prevent and treat nausea, vomiting, and dizziness associated with motion sickness, and vertigo.

For oral dosage form (tablets):

• Adults and teenagers—The usual dose is 50 milligrams (mg) thirty minutes before travel. The dose may be repeated every four to six hours if needed. Not more than 200 mg should be taken in one day.
• Children 6 to 12 years of age—The usual dose is 25 mg thirty minutes before travel. The dose may be repeated every six to eight hours if needed. Not more than 75 mg should be taken in one day.
• Children up to 6 years of age—Use and dose must be determined by your doctor.

- "Meclizine, Buclizine, and Cyclizine"

Contraindicated in hypersensitivity. Caution in glaucoma, urinary retention, GI obstruction, liver or kidney disease, chronic obstructive pulmonary disease (COPD), seizure disorder.

Caution in heart failure.

Additive effects with alcohol and other CNS depressants, anticholinergics, some antidepressants (e.g., tricyclic antidepressants) and use of more than one antihistamine. Antihistamine effects may be potentiated by monamine oxidase inhibitors. Antacids may impair absorption of antihistamines.

Caution when operating machinery, driving a car, or engaging in underwater sports. Take with food or milk to reduce nausea.