Dimenhydrinate is used to prevent and treat nausea, vomiting, and dizziness caused by motion sickness. Dimenhydrinate is in a class of medications called antihistamines. It works by preventing problems with body balance.

Dimenhydrinate comes as a tablet and chewable tablet to take by mouth with or without food. To prevent motion sickness, the first dose should be taken 30 minutes to 1 hour before you travel or begin motion activity. Adults and children older than age 12 may usually take dimenhydrinate every 4 to 6 hours as needed to prevent or treat motion sickness. Children under age 12 may usually be given dimenhydrinate every 6 to 8 hours as needed to prevent or treat motion sickness. Follow the directions on the package carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take dimenhydrinate exactly as directed. Do not take more or less of it or take it more often than directed by the package label.

Do not give dimenhydrinate to children younger than 2 years of age unless your doctor has told you to do so. - "Dimenhydrinate"

Contraindicated in hypersensitivity. Caution in glaucoma, urinary retention, GI obstruction, liver or kidney disease, chronic obstructive pulmonary disease (COPD), seizure disorder.

Should not be used in children <2 yr.

Additive effects with alcohol and other CNS depressants, anticholinergics, some antidepressants (e.g., tricyclic antidepressants) and use of more than one antihistamine. Antihistamine effects may be potentiated by monamine oxidase inhibitors. Antacids may impair absorption of antihistamines.

May block effectiveness of apomorphine.

Caution when operating machinery, driving a car, or engaging in underwater sports. Take with food or milk to reduce nausea.

FDA Pregnancy category B.